In English


The Regional Health Technology Assessment Centre(HTA-centrum)  Region Västra Götaland, has the task to make statements on HTA reports carried out in VGR.

The statement should summarise the question at issue, level of evidence, efficacy, risks, and economical and ethical aspects of the particular health technology that has been assessed in the Regional activity-based HTA.
Health technology assessment (HTA) is the systematic evaluation of properties, effects, and/or impacts of health care technologies, i.e. interventions that may be used to promote health, to prevent, diagnose or treat disease or for rehabilitation or long-term care. It may address the direct, intended consequences of technologies as well as their indirect, unintended consequences. Its main purpose is to inform technology-related policymaking in health care.

To evaluate the quality of evidence the Centre of Health Technology Assessment in Region Västra Götaland is currently using the GRADE system, which has been developed by a widely representative group of international guideline developers.  According to GRADE the level of evidence is graded in four categories:

High quality of evidence =      (GRADEÅÅÅÅ)
Moderate quality of evidence =  (GRADEÅÅŁ)           
Low quality of evidence =           (GRADE ÅŁ)          
Very low quality of evidence  (GRADE Ł)

In GRADE there is also a system to rate the strength of recommendation of a technology as either “strong” or “weak”. This is presently not used by the Centre of Health Technology Assessment in Region Västra Götaland. However, the assessments still offer some guidance to decision makers in the health care system. If the level of evidence of a positive effect of a technology is of high or moderate quality it most probably qualifies to be used in routine medical care. If the level of evidence is of low quality the use of the technology may be motivated provided there is an acceptable balance between benefits and risks, cost-effectiveness and ethical considerations. Promising technologies, but a very low quality of evidence, motivate further research but should not be used in everyday routine clinical work.

For any other questions or comments, please contact:

Christina Bergh, Professor, MD.
Head of HTA-centrum

Mobile phone: +46 736 88 93 25
or HTA-centrum

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Röda Stråket 8
Sahlgrenska Universitetssjukhuset
SE- 413 45  Gothenburg

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Viva la evidence - lyssna och njut !
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Christina Bergh
Professor, chef HTA-centrum

Pernilla Brown
0708-43 92 30